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. 2021 Aug 5;16(8):e0255732.
doi: 10.1371/journal.pone.0255732. eCollection 2021.

Acupuncture for glucose and lipid metabolic disorders of polycystic ovarian syndrome: A systematic review protocol

Yang Wu  1 , Tao Peng  1 , Yu Chen  2 , Li Huang  3 , Bisong He  1 , Shaobin Wei  3
Affiliations

Acupuncture for glucose and lipid metabolic disorders of polycystic ovarian syndrome: A systematic review protocol

Yang Wu et al. PLoS One. .

Abstract

Background: Polycystic ovary syndrome (PCOS) is a common gynecological disease that is often accompanied by some metabolic abnormality such as insulin resistance and dyslipidemia. As a non-pharmacological therapy, acupuncture is widely used for the treatment of PCOS, but the effectiveness for insulin resistance and lipid metabolic disorder remains controversial.

Objectives: To assess the effectiveness and safety of acupuncture for insulin resistance and lipid metabolic disorder of women with PCOS.

Search methods: Eight databases will be searched from inception to June 2021, three clinical trial registration platforms will be searched for relevant trials.

Selection criteria: Randomized controlled trials (RCTs) of acupuncture therapy for insulin resistance and lipid metabolic of PCOS will be included.

Data collection and analysis: Study screening, data collection, and analysis will be performed by two or more reviewers independently. We will calculate mean difference (MD), standard mean difference (SMD) with 95% confidence intervals (CIs). Data synthesis will be performed with RevMan V.5.3 software and with Stata V.15.0 software when necessary.

Prospero registration number: CRD42020177846.

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Conflict of interest statement

The authors have declared that no competing interests exist.

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