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Case Reports
. 2022 Jan;10(1):14-17.
doi: 10.1016/j.jvsv.2021.07.009. Epub 2021 Aug 2.

Three cases of acute venous thromboembolism in females after vaccination for coronavirus disease 2019

Elizabeth A Andraska  1 , Rohan Kulkarni  2 , Mirnal Chaudhary  2 , Ulka Sachdev  2
Affiliations
Case Reports

Three cases of acute venous thromboembolism in females after vaccination for coronavirus disease 2019

Elizabeth A Andraska et al. J Vasc Surg Venous Lymphat Disord. 2022 Jan.

Abstract

Since December 2020, four vaccines for SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) have been developed, and three have been approved for immediate use in the United States. Two are mRNA vaccines, and one uses a viral vector mechanism. Thrombotic complications have been reported after vaccine administration, which were primarily cerebral sinus thromboses after administration of the viral vector vaccines. To the best of our knowledge, we are the first to report venous thrombotic complications within days of administration of the mRNA-1273 (Moderna) vaccine. We present a series of three women who developed venous thromboembolism after RNA-1273 vaccination at a single healthcare system.

Keywords: COVID-19; Deep vein thrombosis; Pulmonary embolism; Venous thromboembolism.

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Figures

Fig 1
Fig 1
Computed tomography scan showing bilateral segmental pulmonary embolism (PE; arrows) in a 25-year-old woman.
Fig 2
Fig 2
Computed tomography scan showing bilateral segmental pulmonary embolism (PE; arrows) in a 77-year-old woman.
Fig 3
Fig 3
Computed tomography scan showing left common femoral venous thrombosis (arrow) in an 85-year-old woman.
See this image and copyright information in PMC

Comment in

  • Reply.
    Andraska EA, Sachdev U. Andraska EA, et al. J Vasc Surg Venous Lymphat Disord. 2022 Jan;10(1):285. doi: 10.1016/j.jvsv.2021.09.008. J Vasc Surg Venous Lymphat Disord. 2022. PMID: 34920849 Free PMC article. No abstract available.
  • Acute venous thromboembolism after COVID-19 vaccination.
    Mungmunpuntipantip R, Wiwanitkit V. Mungmunpuntipantip R, et al. J Vasc Surg Venous Lymphat Disord. 2022 Jan;10(1):285. doi: 10.1016/j.jvsv.2021.08.024. J Vasc Surg Venous Lymphat Disord. 2022. PMID: 34920850 Free PMC article. No abstract available.

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