Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Aug 17;42(31):2990-2994.
doi: 10.1093/eurheartj/ehab457.

The importance of achieving sex- and gender-based equity in clinical trials: a call to action

Jeske van Diemen  1 , Petra Verdonk  2 , Alaide Chieffo  3 , Evelyn Regar  4 , Fina Mauri  5 , Vijay Kunadian  6 , Garima Sharma  7 , Roxana Mehran  8 , Yolande Appelman  9
Affiliations

The importance of achieving sex- and gender-based equity in clinical trials: a call to action

Jeske van Diemen et al. Eur Heart J. .

Erratum in

No abstract available

PubMed Disclaimer

Figures

Graphical Abstract
Graphical Abstract
Recommendations for sex and gender balanced (cardiovascular) medical trials.
None
See this image and copyright information in PMC

References

    1. Vogel B, Acevedo M, Appelman Y, Bairey Merz CN, Chieffo A, Figtree GA, Guerrero M, Kunadian V, Lam CSP, Maas AHEM, Mihailidou AS, Olszanecka A, Poole JE, Saldarriaga C, Saw J, Zühlke L, Mehran R. The Lancet Women and Cardiovascular Disease Commission: reducing the global burden by 2030. Lancet 2021;397:2385–2438. - PubMed
    1. Mosca L, Benjamin EJ, Berra K, Bezanson JL, Dolor RJ, Lloyd-Jones DM, Newby LK, Pina IL, Roger VL, Shaw LJ, Zhao D, Beckie TM, Bushnell C, D'Armiento J, Kris-Etherton PM, Fang J, Ganiats TG, Gomes AS, Gracia CR, Haan CK, Jackson EA, Judelson DR, Kelepouris E, Lavie CJ, Moore A, Nussmeier NA, Ofili E, Oparil S, Ouyang P, Pinn VW, Sherif K, Smith SC Jr., Sopko G, Chandra-Strobos N, Urbina EM, Vaccarino V, Wenger NK. Effectiveness-based guidelines for the prevention of cardiovascular disease in women—2011 update: a guideline from the American Heart Association. Circulation 2011;123:1243–1262. - PMC - PubMed
    1. Scott PE, Unger EF, Jenkins MR, Southworth MR, McDowell TY, Geller RJ, Elahi M, Temple RJ, Woodcock J. Participation of women in clinical trials supporting FDA approval of cardiovascular drugs. J Am Coll Cardiol 2018;71:1960–1969. - PubMed
    1. Jin X, Chandramouli C, Allocco B, Gong E, Lam CSP, Yan LL. Women's participation in cardiovascular clinical trials from 2010 to 2017. Circulation 2020;141:540–548. - PubMed
    1. Ding EL, Powe NR, Manson JE, Sherber NS, Braunstein JB. Sex differences in perceived risks, distrust, and willingness to participate in clinical trials: a randomized study of cardiovascular prevention trials. Arch Intern Med 2007;167:905–912. - PubMed

Publication types

LinkOut - more resources