Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Aug;96(8):2279-2281.
doi: 10.1016/j.mayocp.2021.06.011. Epub 2021 Jun 25.

How Safe Is COVID-19 Convalescent Plasma?

Massimo Franchini  1 , Mario Cruciani  2
Affiliations
Comment

How Safe Is COVID-19 Convalescent Plasma?

Massimo Franchini et al. Mayo Clin Proc. 2021 Aug.
No abstract available

PubMed Disclaimer

Figures

Figure
Figure
Forest plots of comparison of convalescent plasma (CP) vs standard treatment. A, Outcome: all adverse reactions. Data are from 8 randomized clinical trials (RCTs) and 1 non-RCT. B, Outcome: severe adverse reactions.
Figure
Figure
Forest plots of comparison of convalescent plasma (CP) vs standard treatment. A, Outcome: all adverse reactions. Data are from 8 randomized clinical trials (RCTs) and 1 non-RCT. B, Outcome: severe adverse reactions.
See this image and copyright information in PMC

Comment in

  • In Reply-How Safe Is COVID-19 Convalescent Plasma?
    Joyner MJ, Klompas AM, Klassen SA, Senefeld JW, Fairweather D, Wright RS, Carter RE. Joyner MJ, et al. Mayo Clin Proc. 2021 Aug;96(8):2281-2282. doi: 10.1016/j.mayocp.2021.06.010. Epub 2021 Jun 25. Mayo Clin Proc. 2021. PMID: 34353476 Free PMC article. No abstract available.

Comment on

References

    1. Klassen S.A., Senefeld J.W., Johnson P.W. The effect of convalescent plasma therapy on mortality among patients with COVID-19: systematic review and meta-analysis. Mayo Clin Proc. 2021;96(5):1262–1275. - PMC - PubMed
    1. Joyner M.J., Bruno K.A., Klassen S.A. Safety update: COVID-19 convalescent plasma in 20,000 hospitalized patients. Mayo Clin Proc. 2020;95(9):1888–1897. - PMC - PubMed
    1. Marwah V., Choudhary R., Peter D., Bhati G. Pulmonary thromboembolism post-COVID convalescent plasma therapy: adding fuel to a smoldering fire! Adv Resp Med. 2021;89(3):347–349. - PubMed
    1. Cruciani M., Bongiovanni G., Franchini M. High-titer convalescent plasma therapy for COVID-19 and mortality. Transfusion. 2021;61(6):1988–1990. - PMC - PubMed