Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Sep;62(9):938-40.
doi: 10.1136/adc.62.9.938.

Acarboxyprothrombin concentration [corrected] after oral prophylactic vitamin K

R von Kries  1 , S Kreppel, A Becker, R Tangermann, U Göbel
Affiliations

Acarboxyprothrombin concentration [corrected] after oral prophylactic vitamin K

R von Kries et al. Arch Dis Child. 1987 Sep.

Erratum in

  • Arch Dis Child 1987 Dec;62(12):1293

Abstract

The effect of prophylaxis with oral vitamin K (1 mg vitamin K1 given with the first feed) on the rate of detection of acarboxyprothrombin (PIVKA II) and factor II clotting concentration [corrected] were analysed. Introducing such prophylaxis reduced the rates of detection of PIVKA II concentration [corrected] on day 5 from 48% to zero. None of the babies given prophylaxis had factor II clotting concentration [corrected] below 40%, compared with 34 of 95 babies not given prophylaxis. This study has important implications in the prophylaxis of both classical and late onset haemorrhagic disease of the newborn.

PubMed Disclaimer

References

    1. Thromb Diath Haemorrh. 1974 Dec 31;32(2-3):510-8 - PubMed
    1. Lancet. 1985 May 4;1(8436):1035 - PubMed
    1. Lancet. 1985 Aug 3;2(8449):242-4 - PubMed
    1. Arch Dis Child. 1985 Sep;60(9):814-8 - PubMed
    1. Arch Dis Child. 1985 Dec;60(12):1203-4 - PubMed

Publication types

LinkOut - more resources