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. 2022 Jan;18(1):e117-e128.
doi: 10.1200/OP.20.01077. Epub 2021 Aug 6.

Derivation and Validation of the Cancer READMIT Score: A Readmission Risk Scoring System for Patients With Solid Tumor Malignancies

Joanna-Grace M Manzano  1 , Heather Lin  2 , Hui Zhao  3 , Josiah Halm  1 , Maria E Suarez-Almazor  3
Affiliations

Derivation and Validation of the Cancer READMIT Score: A Readmission Risk Scoring System for Patients With Solid Tumor Malignancies

Joanna-Grace M Manzano et al. JCO Oncol Pract. 2022 Jan.

Abstract

Purpose: Readmissions for the medical treatment of cancer have traditionally been excluded from readmission measures under the Hospital Readmissions Reduction Program. Patients with cancer often have higher readmission rates and may need heightened support to ensure effective care transitions after hospitalization. Estimating readmission risk before discharge may assist in discharge planning efforts and help promote care coordination at time of discharge.

Patients and methods: We developed and validated a readmission risk scoring system among a cohort of adult cancer patients with solid tumor admitted at a comprehensive cancer center. Multivariate logistic regression analysis was used to develop the model. The model's discriminative capacity was evaluated through a receiver operating characteristic curve analysis. We further compared the performance of the developed score with existing risk scores for 30-day readmission.

Results: The 30-day unplanned readmission rate in the total cohort was 16.0% (n = 1,078 of 6,720). After multivariate analysis, Cancer site, Recent emergency room visit within 30 days, non-English primary language, Anemia defined as hemoglobin < 10 g/dL, > 4 Days length of stay during the index admission, unmarried Marital status, Increased white blood cell count > 11 × 109/L, and distant Tumor spread were significantly associated with risk of unplanned 30-day readmission. The derived score, which we call the Cancer READMIT score, had modest discriminatory performance in predicting readmissions (area under the curve for the model receiver operating characteristic curve = 0.647).

Conclusion: The Cancer READMIT score was able to predict 30-day unplanned readmissions to our institution with fairly modest performance. External validation of our derived risk scoring system is recommended.

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Figures

FIG 1.
FIG 1.
ROC curves for cancer READMIT score, LACE index, and Hospital score. ROC, receiver operating characteristic.
FIG A1.
FIG A1.
Calibration plot for derivation cohort.
FIG A2.
FIG A2.
Calibration plot for validation cohort.
See this image and copyright information in PMC

References

    1. Wasfy JH, Zigler CM, Choirat C, et al. : Readmission rates after passage of the hospital readmissions reduction Program: A pre-post analysis. Ann Intern Med 166:324-331, 2017 - PMC - PubMed
    1. QualityNet : Readmission Measures. CMS.gov, 2020
    1. Centers for Medicare and Medicaid Services, HHS : Federal Register May 7, 2018 Proposed Rules. govinfo.gov. pp 20504-20506
    1. Schmidt CR, Hefner J, McAlearney AS, et al. : Development and prospective validation of a model estimating risk of readmission in cancer patients. J Surg Oncol 117:1113-1118, 2018 - PubMed
    1. Bell JF, Whitney RL, Reed SC, et al. : Systematic review of hospital readmissions among patients with cancer in the United States. Oncol Nurs Forum 44:176-191, 2017 - PubMed

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