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Case Reports
. 2021 Jul 24;18(15):7851.
doi: 10.3390/ijerph18157851.

Rhabdomyosarcoma of the Cervix in a Post-Menopausal Woman-An Unparalleled Phenomenon

Jakub Pawlik  1 , Weronika Pawlik  1 , Dorota Branecka-Woźniak  2 , Katarzyna Kotrych  3 , Aneta Cymbaluk-Płoska  1
Affiliations
Case Reports

Rhabdomyosarcoma of the Cervix in a Post-Menopausal Woman-An Unparalleled Phenomenon

Jakub Pawlik et al. Int J Environ Res Public Health. .

Abstract

Rhabdomyosarcoma of the cervix is a soft tissue sarcoma that usually occurs in young women. It is very rare in adulthood. We discuss symptoms, the process of diagnosis of rhabdomyosarcoma embryonale of the cervix in a 61-year-old women and differences in treatment dependent on patient's age. A 61-year-old woman with symptoms such as palpable mass in the external cervical opening and post-menopausal hemorrhaging was admitted to the oncology ward where excision of the polyp was performed. Embryonal rhabdomyosarcoma (ERMS) was diagnosed by histopathological examination of obtained tissues. The diagnosis was complemented by chest computed tomography and pelvis magnetic resonance imaging to exclude metastases. A Wertheim-Meigs operation and excision of the ovaries, the fallopian tubes and the surrounding tissue was performed in the course of treatment. In the patient's follow-up of 25 months to date, there have been no signs of recurrence or symptoms connected to ERMS. Based on the therapeutic outcome, the decision to limit the treatment to a surgical resection was adequate for a post-menopausal patient. Because of the rarity of ERMS in the post-menopausal age, we think that the patient should be carefully followed up to further examine this issue and develop diagnostic and treatment guidelines.

Keywords: cervix; gynecology; neoplasm; oncology; post-menopausal; rhabdomyosarcoma; sarcoma; uterus.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Histopathological images of the excised polyp (A) in 10× magnification. (B) in 20× magnification. Arrows show spindle and round pleomorphic cells with hyperchromatic nuclei and scant cytoplasm.
Figure 2
Figure 2
A preoperative MRI of the pelvis in (A) axial and (B) sagittal projection. Both show the presence of myomas in the uterus. Arrows show myomas in the uterus.
Figure 3
Figure 3
A postoperative MRI of the pelvis in axial projection, performed 18 months after the Wertheim–Meigs operation. A vaginal stump is visible. No signs of recurrence are present.
See this image and copyright information in PMC

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