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. 2021 Oct;101(2):115485.
doi: 10.1016/j.diagmicrobio.2021.115485. Epub 2021 Jul 10.

Direct antimicrobial susceptibility testing (AST) from positive blood cultures using Microscan system for early detection of bacterial resistance phenotypes

A Quirino  1 , N Marascio  1 , C Peronace  1 , L Gallo  1 , G S Barreca  1 , A Giancotti  1 , A G Lamberti  1 , M Colosimo  2 , P Minchella  2 , E M Trecarichi  3 , C Torti  3 , M C Liberto  1 , G Matera  4
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Direct antimicrobial susceptibility testing (AST) from positive blood cultures using Microscan system for early detection of bacterial resistance phenotypes

A Quirino et al. Diagn Microbiol Infect Dis. 2021 Oct.

Abstract

Antimicrobial Susceptibility Testing is mandatory for Bloodstream Infections management in order to establish appropriate antimicrobial therapy. Herein we evaluated new approach based on AST results directly from positive blood cultures, using Microscan WA to carry out rapid phenotypical profile of antibiotic resistance. Our investigations allow to reduce time versus traditional results.

Keywords: Bacterial resistance phenotypes; Rapid antimicrobial susceptibility testing (AST); Sepsis.

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