Caution When Comparing the Impact of Corticosteroids in COVID-19

Marco Confalonieri¹, Francesco Salton², Paola Confalonieri², Bram Rochwerg³, G Umberto Meduri⁴

Affiliations

¹ Pulmonology Department, University Hospital of Cattinara, and the Department of Medical Surgical and Health Sciences, University of Trieste, Trieste, Italy. Electronic address: mconfalonieri@units.it.
² Pulmonology Department, University Hospital of Cattinara, and the Department of Medical Surgical and Health Sciences, University of Trieste, Trieste, Italy.
³ Department of Medicine, Division of Critical Care, McMaster University, Hamilton, ON, Canada.
⁴ Departments of Medicine, Pulmonary, Critical Care, and Sleep Medicine Service, Memphis Veterans Affairs Medical Center, Memphis, TN.

PMID: 34366052
PMCID: PMC8339403
DOI: 10.1016/j.chest.2021.04.026

Comment

Caution When Comparing the Impact of Corticosteroids in COVID-19

Marco Confalonieri et al. Chest. 2021 Aug.

. 2021 Aug;160(2):e243-e244.

doi: 10.1016/j.chest.2021.04.026.

Authors

Marco Confalonieri¹, Francesco Salton², Paola Confalonieri², Bram Rochwerg³, G Umberto Meduri⁴

Affiliations

¹ Pulmonology Department, University Hospital of Cattinara, and the Department of Medical Surgical and Health Sciences, University of Trieste, Trieste, Italy. Electronic address: mconfalonieri@units.it.
² Pulmonology Department, University Hospital of Cattinara, and the Department of Medical Surgical and Health Sciences, University of Trieste, Trieste, Italy.
³ Department of Medicine, Division of Critical Care, McMaster University, Hamilton, ON, Canada.
⁴ Departments of Medicine, Pulmonary, Critical Care, and Sleep Medicine Service, Memphis Veterans Affairs Medical Center, Memphis, TN.

PMID: 34366052
PMCID: PMC8339403
DOI: 10.1016/j.chest.2021.04.026

No abstract available

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Comment in

Response.
Cano E, Fonseca Fuentes X, Corsini Campioli C, O'Horo JC, Abu Saleh O, Temesgen Z. Cano E, et al. Chest. 2021 Aug;160(2):e244. doi: 10.1016/j.chest.2021.04.028. Chest. 2021. PMID: 34366053 No abstract available.

Comment on

Impact of Corticosteroids in Coronavirus Disease 2019 Outcomes: Systematic Review and Meta-analysis.
Cano EJ, Fonseca Fuentes X, Corsini Campioli C, O'Horo JC, Abu Saleh O, Odeyemi Y, Yadav H, Temesgen Z. Cano EJ, et al. Chest. 2021 Mar;159(3):1019-1040. doi: 10.1016/j.chest.2020.10.054. Epub 2020 Oct 28. Chest. 2021. PMID: 33129791 Free PMC article.

References

1. RECOVERY Collaborative Group. Horby P., Lim W.S. Dexamethasone in hospitalized patients with Covid-19: preliminary report. N Engl J Med. 2021;384(8):693–704. - PMC - PubMed
1. Sterne J.A.C., The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group Association between administration of systemic corticosteroids and mortality among critically ill patients with COVID-19: A meta-analysis. JAMA. 2020;324(13):1330–1341. - PMC - PubMed
1. Rochwerg B., Siemieniuk R.A., Agoritsas T. A living WHO guideline on drugs for covid-19. BMJ. 2020;370:m3379. - PubMed
1. Cano E.J., Fonseca Fuentes X., Corsini Campioli C. Impact of corticosteroids in coronavirus disease 2019 outcomes: systematic review and meta-analysis. Chest. 2021;159(3):1019–1040. - PMC - PubMed
1. Meduri G.U., Annane D., Confalonieri M. Pharmacological principles guiding prolonged glucocorticoid treatment in ARDS. Intensive Care Med. 2020 In press. - PMC - PubMed

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Caution When Comparing the Impact of Corticosteroids in COVID-19

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Caution When Comparing the Impact of Corticosteroids in COVID-19

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