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. 2020 Feb 4;2(1):100039.
doi: 10.1016/j.infpip.2020.100039. eCollection 2020 Mar.

Burkholderia cepacia complex outbreak originating from contaminated wash gloves

Elia Lo Priore  1 , Stefano Bernasconi  2 , Hervè Schlotterbeck  3 , Helena Mb Seth-Smith  4   5 , Adrian Egli  4   5 , Gladys Martinetti  6 , Carlo Balmelli  1
Affiliations

Burkholderia cepacia complex outbreak originating from contaminated wash gloves

Elia Lo Priore et al. Infect Prev Pract. .

Abstract

Burkholderia cepacia complex isolates were detected from four patients who were admitted to the heart centre of southern Switzerland, between April and June 2019. An outbreak investigation was conducted. The three available patient samples were whole genome sequenced, showing that they all are Burkholderia cepacia species, and that two are identical. Isolates grown from sealed packages of disinfectant-free wash gloves used for personal hygiene were also genomically identical. The wash gloves appear to be the origin of the outbreak, contamination of which most likely occurred at the manufacturing site.

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Conflict of interest statement

All authors report no conflicts of interest relevant to this article.

Figures

Figure 1
Figure 1
Whole genome SNP phylogeny of the isolates. The isolates from Patients 1 and 2, and Gloves 1 and 2 are identical across the whole genome. The genome of the isolate from Patient 1 (in italics) was used as the reference, and Burkholderia cepacia reference strain ATCC 25416 added for context. The scale shows the number of SNP differences, and the phylogeny is not rooted. The group of isolates including Patient 1, Patient 2, Glove 1 and Glove 2 are identical at the SNP level. This analysis was performed in CLC genomics workbench (v10.1.1).
See this image and copyright information in PMC

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