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Case Reports
. 2021 Nov;42(11):4419-4420.
doi: 10.1007/s10072-021-05515-5. Epub 2021 Aug 9.

Post-COVID-19 neurocandidiasis

Miguel A Miranda  1 , Sandra C Sousa  2 , Vera L Montes  2
Affiliations
Case Reports

Post-COVID-19 neurocandidiasis

Miguel A Miranda et al. Neurol Sci. 2021 Nov.

Abstract

Associated with a significant morbidity and mortality, neurocandidiasis affects severely immunocompromised patients, especially if recently treated with antibiotics or corticosteroids. We present the case of a 70-year-old man admitted to an intensive care unit due to a Sars-Cov-2 pneumonia, with fever, coma, and multifocal neurological deficits reported 13 days after extubation. After isolation of Candida albicans in both urine and blood cultures and a brain MRI with multiple gadolinium-enhanced ring lesions, a diagnosis of neurocandidiasis was assumed and aggressive antifungal therapy started. During treatment, the patient developed a hospital-acquired pneumonia with fatal outcome.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Multiple small gadolinium-enhancing ring lesions, with cortical-subcortical and basal ganglia dispersion, suggestive of neurocandidiasis microabcesses. (1) Axial T2w. (2) Coronal T2w. (3) Sagittal T2w. (4) Axial T2*w gradient echo. (5) DWI. (6) ADC. (7, 8) Gadolinium-enhanced T1w, axial and coronal, respectively
See this image and copyright information in PMC

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