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Case Reports
. 2021 Oct 18;65(11):e0092421.
doi: 10.1128/AAC.00924-21. Epub 2021 Aug 9.

Extensively Drug-Resistant Acinetobacter baumannii Nosocomial Pneumonia Successfully Treated with a Novel Antibiotic Combination

Noor Zaidan  1 , J Patrik Hornak  2 , David Reynoso  2
Affiliations
Case Reports

Extensively Drug-Resistant Acinetobacter baumannii Nosocomial Pneumonia Successfully Treated with a Novel Antibiotic Combination

Noor Zaidan et al. Antimicrob Agents Chemother. .

Abstract

Extremely drug-resistant (XDR) Acinetobacter baumannii causes challenging nosocomial infections. We report the case of a patient with XDR A. baumannii pneumonia and septic shock successfully treated with cefiderocol and a novel antibiotic obtained via expanded access protocol. With focused research and drug development efforts, the poor outcomes associated with these infections may be mitigated.

Keywords: Acinetobacter baumanii; Gram-negative bacteria; Gram-negative resistance; antibiotic resistance; antimicrobial agents; beta-lactamases; beta-lactams; durlobactam; nosocomial infections; novel antibiotics; sulbactam-durlobactam.

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Figures

FIG 1
FIG 1
Chest radiographs on hospital days 2 (left) and 13 (right) showing development of multifocal ventilator-associated pneumonia during hospitalization.
See this image and copyright information in PMC

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