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. 1978 Jan;13(1):4-6.
doi: 10.1128/AAC.13.1.4.

Hemodialysis-associated infections: treatment with cephapirin

S J Berman, W H Boughton, J G Sugihara, E G Wong, A W Siemsen

Hemodialysis-associated infections: treatment with cephapirin

S J Berman et al. Antimicrob Agents Chemother. 1978 Jan.

Abstract

Large doses of cephapirin (50 mg/kg) administered during the first and last half hours of routine hemodialysis produced effective antimicrobial serum concentrations for 48 h. Repetitive administration during five successive hemodialysis sessions did not result in accumulation or accelerated metabolism of cephapirin. Ten infectious episodes in nine patients were treated in this manner with good clinical results and no toxicity.

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