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. 2021 Dec 1;40(12):e509-e511.
doi: 10.1097/INF.0000000000003285.

Long COVID in Children: Observations From a Designated Pediatric Clinic

Liat Ashkenazi-Hoffnung  1   2 , Einat Shmueli  1   2 , Shay Ehrlich  1   2 , Adi Ziv  1   2 , Ophir Bar-On  1   2 , Einat Birk  1   2 , Alexander Lowenthal  1   2 , Dario Prais  1   2
Affiliations

Long COVID in Children: Observations From a Designated Pediatric Clinic

Liat Ashkenazi-Hoffnung et al. Pediatr Infect Dis J. .

Abstract

Systematic data are lacking on pediatric long COVID. This study prospectively assessed 90 children with persistent symptoms who presented to a designated multidisciplinary clinic for long COVID. In nearly 60%, symptoms were associated with functional impairment at 1-7 months after the onset of infection. A comprehensive structured evaluation revealed mild abnormal findings in approximately half the patients, mainly in the respiratory aspect.

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Conflict of interest statement

The authors have no funding or conflicts of interest to disclose.

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References

    1. Carfì A, Bernabei R, Landi F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent symptoms in patients after acute COVID-19. JAMA. 2020;324:603–605. - PMC - PubMed
    1. Tenforde MW, Kim SS, Lindsell CJ, et al. ; IVY Network Investigators; CDC COVID-19 Response Team; IVY Network Investigators. Symptom duration and risk factors for delayed return to usual health among outpatients with COVID-19 in a Multistate Health Care Systems Network - United States, March-June 2020. MMWR Morb Mortal Wkly Rep. 2020;69:993–998. - PMC - PubMed
    1. Ludvigsson JF. Case report and systematic review suggest that children may experience similar long-term effects to adults after clinical COVID-19. Acta Paediatr. 2021;110:914–921. - PMC - PubMed
    1. National Institute of Health severity COVID-19 criteria. 2021. Available from: https://www.covid19treatmentguidelines.nih.gov/overview/clinical-spectrum/. Accessed July 5, 2021.
    1. Rubin L, Honovich M, Stahl Z, et al. . Israeli Ministry of Health. Growth measurements of Israeli schoolchildren, 2011–2012. 2013. Available from: https://www.health.gov.il/publicationsfiles/gdila-school-2010-2012.pdf. Accessed July 6, 2021.