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Review
. 2021 Jul 5;13(7):2314.
doi: 10.3390/nu13072314.

Monoclonal Antibodies in Treating Food Allergy: A New Therapeutic Horizon

Sara Manti  1 , Giulia Pecora  1 , Francesca Patanè  1 , Alessandro Giallongo  1 , Giuseppe Fabio Parisi  1 , Maria Papale  1 , Amelia Licari  2 , Gian Luigi Marseglia  2 , Salvatore Leonardi  1
Affiliations
Review

Monoclonal Antibodies in Treating Food Allergy: A New Therapeutic Horizon

Sara Manti et al. Nutrients. .

Abstract

Food allergy (FA) is a pathological immune response, potentially deadly, induced by exposure to an innocuous and specific food allergen. To date, there is no specific treatment for FAs; thus, dietary avoidance and symptomatic medications represent the standard treatment for managing them. Recently, several therapeutic strategies for FAs, such as sublingual and epicutaneous immunotherapy and monoclonal antibodies, have shown long-term safety and benefits in clinical practice. This review summarizes the current evidence on changes in treating FA, focusing on monoclonal antibodies, which have recently provided encouraging data as therapeutic weapons modifying the disease course.

Keywords: adults; biologics; children; food allergy; monoclonal antibodies.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Developmental timing of monoclonal antibodies used for treating allergic disorders.
See this image and copyright information in PMC

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