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Clinical Trial
. 1978 Feb;37(1):85-8.
doi: 10.1136/ard.37.1.85.

Double-blind trial of naproxen and phenylbutazone in ankylosing spondylitis

F Van Gerwen, J K Van der Korst, F W Gribnau
Clinical Trial

Double-blind trial of naproxen and phenylbutazone in ankylosing spondylitis

F Van Gerwen et al. Ann Rheum Dis. 1978 Feb.

Abstract

In a double-blind double-placebo crossover study naproxen (500-750 mg daily) was found to be equivalent to phenylbutazone (400-600 mg daily) in the control of disease activity in 20 patients suffering from ankylosing spondylitis during a two times 5-week trial period. No serious side effects were observed during the trial period. Gastric complaints occurred twice as often under phenylbutazone as under naproxen.

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