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Clinical Trial
. 1978 Feb;37(1):89-92.
doi: 10.1136/ard.37.1.89.

Sulindac. Trials of a new anti-inflammatory drug

E C Huskisson, J Scott
Clinical Trial

Sulindac. Trials of a new anti-inflammatory drug

E C Huskisson et al. Ann Rheum Dis. 1978 Feb.

Abstract

Trials in patients with rheumatoid arthritis and osteoarthritis showed sulindac to be an analgesic with anti-inflammatory properties and at least as effective as aspirin. It was effective within 24 hours in doses of 300-400 mg daily. It had the advantages of twice daily administration and a lower incidence of gastric side effects than aspirin. Constipation, usually mild, occurred in 20-30% of cases. Like other anti-inflammatory drugs, it was effective in only a proportion of the patients.

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References

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