Secondary metabolites from Fusarium. Two new modified trichothecenes from Fusarium sporotrichioides MC-72083
- PMID: 3437285
- DOI: 10.1021/np50053a021
Secondary metabolites from Fusarium. Two new modified trichothecenes from Fusarium sporotrichioides MC-72083
Abstract
Two new, relatively non-toxic, secondary metabolites characterized as 8 alpha- and 8 beta-hydroxysambucoin [1] and [2], isolated from the toxigenic fungus Fusarium sporotrichioides MC-72083 are reported. The structural assignments were established by spectral data with 1H-nmr studies (COSY, dnOes) playing a key role in establishing the stereochemistry in 1 and 2. The isolation of 14 known trichothecenes produced by this fungus is also discussed.
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