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Case Reports
. 2021 Aug 10;14(8):e245282.
doi: 10.1136/bcr-2021-245282.

Rare intracranial EWSR1-rearranged myxoid mesenchymal tumour in a teenager

Jason W Adams  1 , Denise Malicki  2 , Michael Levy  3 , John Ross Crawford  4
Affiliations
Case Reports

Rare intracranial EWSR1-rearranged myxoid mesenchymal tumour in a teenager

Jason W Adams et al. BMJ Case Rep. .
No abstract available

Keywords: CNS cancer; neuro-oncology; neuroimaging; pathology.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Neuroimaging features of central nervous system mixed mesenchymal tumour. MRI reveals a large left posterior tumour with surrounding vasogenic oedema on T2-weighted sequences (A), with no evidence of reduced diffusivity (B) or susceptibility-weighted artefact (C) that shows homogeneous enhancement on T1-post gadolinium weighted sequences (D).
Figure 2
Figure 2
Neuropathology of central nervous system mixed mesenchymal tumour. H&E stained section reveals a spindle cell proliferation of low cellularity with angulate, hyperchromatic nuclei and thin strands of cytoplasm separated by an abundant myxoid background. Scattered ‘rosette-like’ structures with a central core of densely eosinophilic, hypocellular collagenous material. Mitotic activity is inconspicuous. Reticulin stain showed abundant background deposition around tumour cells and diffuse positivity for CD99 (not shown) consistent with a diagnosis of mixed mesenchymal tumour.
See this image and copyright information in PMC

References

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