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Review
. 2021;9(3):77-82.
doi: 10.1007/s40135-021-00271-3. Epub 2021 Aug 5.

Impact of SARS-CoV-2 on Ocular Surface Pathology and Treatment Practices: a Review

Sila Bal  1 , James Chodosh  1 , Nandini Venkateswaran  1   2
Affiliations
Review

Impact of SARS-CoV-2 on Ocular Surface Pathology and Treatment Practices: a Review

Sila Bal et al. Curr Ophthalmol Rep. 2021.

Abstract

Purpose of review: The ocular surface is a potential site of ocular involvement by SARS-CoV-2 infection. We performed a review of the literature to understand the pathogenesis of SARS-CoV-2 disease manifestations on the ocular surface as well as to elucidate emerging treatment patterns and practice changes during the COVID-19 pandemic.

Recent findings: The ocular manifestations of SARS-CoV-2 are likely limited to a mild and transient conjunctivitis. Other manifestations have not been validated in larger cohorts. Ocular surface tissue should be considered potentially infectious due to the presence of host receptors on surface tissues. The availability of donor tissue in lower-middle income countries has been greatly impacted by the pandemic and would benefit from further investigation into transmissibility through donor tissue.

Summary: Transmission of SARS-CoV-2 through the ocular surface has yet to be confirmed. The most common ocular manifestation is a mild conjunctivitis. Ocular surface surgeons face specific challenges in the use of donor tissues and aerosolizing procedures and have adapted practice patterns accordingly.

Keywords: COVID-19 eye; COVID-19 ocular surface; Ocular surface pathology COVID-19; SARS-CoV-2 ocular surface.

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Conflict of interest statement

Conflict of InterestThe authors declare no conflict of interest.

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