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. 1987 Dec;7(12):4557-9.
doi: 10.1128/mcb.7.12.4557-4559.1987.

The stem-loop structure at the 3' end of histone mRNA is necessary and sufficient for regulation of histone mRNA stability

N B Pandey  1 , W F Marzluff
Affiliations

The stem-loop structure at the 3' end of histone mRNA is necessary and sufficient for regulation of histone mRNA stability

N B Pandey et al. Mol Cell Biol. 1987 Dec.

Abstract

Chimeric genes were made by fusing mouse histone genes with a human alpha-globin gene. The genes were introduced into mouse L cells and the stability of the chimeric mRNAs was measured when DNA synthesis was inhibited. An mRNA containing all the globin coding sequences and the last 30 nucleotides of the histone mRNA was degraded at the same rate as histone mRNA.

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References

    1. Mol Cell Biol. 1983 Nov;3(11):1920-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1987 Sep;84(17):6189-93 - PubMed
    1. Biochemistry. 1984 Apr 10;23(8):1618-25 - PubMed
    1. Mol Cell Biol. 1984 Oct;4(10):2082-90 - PubMed
    1. Proc Natl Acad Sci U S A. 1985 May;82(9):2834-8 - PubMed

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