Lateral Pelvic Node Metastasis in Locally Advanced Rectal Cancer: Are We Exaggerating or Ignoring?

Affiliations

¹ Colorectal Cancer Center, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. kyuschoi@mail.knu.ac.kr.

Editorial

Gyu-Seog Choi. Ann Surg Oncol. 2021 Oct.

. 2021 Oct;28(11):5803-5804.

doi: 10.1245/s10434-021-10558-1. Epub 2021 Aug 11.

¹ Colorectal Cancer Center, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. kyuschoi@mail.knu.ac.kr.

No abstract available

References

1. Fujita S, Mizusawa J, Kanemitsu Y, et al. Colorectal Cancer Study Group of Japan Clinical Oncology Group. Mesorectal excision with or without lateral lymph node dissection for clinical stage II/III lower rectal cancer (JCOG0212): A multicenter, randomized controlled, noninferiority trial. Ann Surg. 2017;266:201–7. - DOI
1. Ogura A, Konishi T, Cunningham C, et al. Lateral Node Study Consortium. Neoadjuvant (Chemo)radiotherapy with total mesorectal excision only is not sufficient to prevent lateral local recurrence in enlarged nodes: Results of the multicenter lateral node study of patients with low cT3/4 rectal cancer. J Clin Oncol. 2019;37:33–43. - DOI
1. Kim TH, Jeong SY, Choi DH, et al. Lateral lymph node metastasis is a major cause of locoregional recurrence in rectal cancer treated with preoperative chemoradiotherapy and curative resection. Ann Surg Oncol. 2008;15:729–37. - DOI
1. Kim HJ, Choi GS, Park JS, et al. Optimal treatment strategies for clinically suspicious lateral pelvic lymph node metastasis in rectal cancer. Oncotarget. 2017;8:100724–33. - DOI
1. Hida K, Nishzaki D, Sumii A, et al.; Japan Society of Laparoscopic Colorectal Surgery. Prognostic impact of lateral pelvic node dissection on the survival of patients in low rectal cancer subgroups based on lymph node size. Ann Surg Oncol. 2021. https://doi.org/10.1245/s10434-021-10312-7 . - DOI - PubMed