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Review
. 2021 Aug 11:374:n1493.
doi: 10.1136/bmj.n1493.

Medication adherence in cardiovascular medicine

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Review

Medication adherence in cardiovascular medicine

Steven T Simon et al. BMJ. .

Abstract

Cardiovascular disease is the leading cause of death globally. While pharmacological advancements have improved the morbidity and mortality associated with cardiovascular disease, non-adherence to prescribed treatment remains a significant barrier to improved patient outcomes. A variety of strategies to improve medication adherence have been tested in clinical trials, and include the following categories: improving patient education, implementing medication reminders, testing cognitive behavioral interventions, reducing medication costs, utilizing healthcare team members, and streamlining medication dosing regimens. In this review, we describe specific trials within each of these categories and highlight the impact of each on medication adherence. We also examine ongoing trials and future lines of inquiry for improving medication adherence in patients with cardiovascular diseases.

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Conflict of interest statement

Competing interests: We have read and understood the BMJ policy on declaration of interests and declare the following interests: STS reports none, AEL reports none, VK reports unrelated research grants from the NIH and Greenwall Foundation, PMH reports research grants from Department of Veterans Affairs, NHLBI, and University of Colorado School of Medicine. His NHLBI grant is focused on medication adherence. He has a research agreement with Bristol Myers Squibb unrelated to medication adherence. He serves as a deputy editor for Circulation: Cardiovascular Quality and Outcomes.

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