[Role of 131I-metaiodobenzylguanidine scintigraphy in the diagnosis of intestinal carcinoids]
[Article in
German]
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- PMID: 3438170
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[Role of 131I-metaiodobenzylguanidine scintigraphy in the diagnosis of intestinal carcinoids]
[Article in
German]
Nuklearmedizin.
1987 Dec.
Abstract
Iodine-131 metaiodobenzylguanidine (131I-MIBG) is concentrated in a variety of neuroendocrine tumors, such as pheochromocytoma and neuroblastoma. Other neuroendocrine tumors from the APUD-cell system such as carcinoid tumors, may possess this uptake capability as well. We investigated 11 patients suffering from intestinal carcinoid with 131I-MIBG in order to determine the value of MIBG scintigraphy in these tumors. MIBG scans were positive in 5 out of 11 patients (45%). False-positive MIBG-scans did not occur. No correlation between MIBG uptake, clinical symptoms and urinary 5-HIAA level could be found.
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