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. 2021 Dec 31;37(1):187-189.
doi: 10.1093/ndt/gfab240.

Immune checkpoint inhibitor-induced thyroiditis is a risk factor for acute and chronic kidney dysfunction

Ian A Strohbehn  1 , Sarah Street  2 , Donald Chute  1 , Harish Seethapathy  1 , Meghan Lee  1 , Rituvanthikaa Seethapathy  1 , Zsofia D Drobni  3   4 , Osama Rahma  5 , Tomas G Neilan  3   6 , Leyre Zubiri  7 , Kerry Reynolds  7 , Meghan E Sise  1
Affiliations

Immune checkpoint inhibitor-induced thyroiditis is a risk factor for acute and chronic kidney dysfunction

Ian A Strohbehn et al. Nephrol Dial Transplant. .
No abstract available

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Figures

FIGURE 1
FIGURE 1
Patient flow and outcomes. Among patients surviving 1 year, Cox proportional hazards models were performed to predict each of the three renal outcomes among patients experiencing thyroiditis within 12 months compared with those who did not develop thyroiditis within 12 months.
See this image and copyright information in PMC

References

    1. Seethapathy H, Zhao S, Chute DF et al. . The incidence, causes, and risk factors of acute kidney injury in patients receiving immune checkpoint inhibitors. Clin J Am Soc Nephrol 2019; 14: 1692–1700 - PMC - PubMed
    1. Chute DF, Zhao S, Strohbehn IA et al. Clinically significant estimated glomerular filtration rate decline is common in patients receiving immune checkpoint inhibitors: implications for long-term cancer survivors. medRxiv.org 2020; doi: 10.1101/2020.12.18.20248471 - DOI
    1. Cortazar FB, Kibbelaar ZA, Glezerman IG et al. . Clinical features and outcomes of immune checkpoint inhibitor-associated AKI: a multicenter study. J Am Soc Nephrol 2020; 31: 435–446 - PMC - PubMed
    1. Manohar S, Ghamrawi R, Chengappa M et al. . Acute interstitial nephritis and checkpoint inhibitor therapy. Kidney360 2020; 1: 16–24 - PMC - PubMed
    1. Seethapathy H, Zhao S, Strohbehn IA et al. . Incidence and clinical features of immune-related acute kidney injury in patients receiving programmed cell death ligand-1 inhibitors. Kidney Int Rep 2020; 5: 1700–1705 - PMC - PubMed

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