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Comment
. 2021 Aug 11;29(8):1213-1216.
doi: 10.1016/j.chom.2021.07.007.

Guardians of the barrier: Microbiota engage AHR in keratinocytes to mantain skin homeostasis

Wisam Alwan  1 , Paola Di Meglio  2
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Guardians of the barrier: Microbiota engage AHR in keratinocytes to mantain skin homeostasis

Wisam Alwan et al. Cell Host Microbe. .
Free article

Abstract

The skin barrier is critical in ensuring homeostasis, yet factors influencing its development, repair, and maintenance are ill-defined. In this issue of Cell Host & Microbe, Uberoi et al. demonstrate the skin microbiota's role in maintaining barrier integrity via AHR signaling in keratinocytes, which has implications for skin disease management.

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