License to LAP
- PMID: 34384524
- DOI: 10.1016/j.chom.2021.07.010
License to LAP
Abstract
Engagement of LC3-associated phagocytosis (LAP) in response to the uptake of certain particles modulates innate immune responses. Now in Cell Host and Microbe, Akoumianaki et al. (2021) show how a regulatory role of IL-6 on LAP may be at the core of susceptibility to secondary infection during severe sepsis.
Copyright © 2021 Elsevier Inc. All rights reserved.
Comment on
-
Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis.Cell Host Microbe. 2021 Aug 11;29(8):1277-1293.e6. doi: 10.1016/j.chom.2021.06.002. Epub 2021 Jul 1. Cell Host Microbe. 2021. PMID: 34214493
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials
