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Case Reports
. 2021 Oct;132(4):e139-e142.
doi: 10.1016/j.oooo.2021.06.019. Epub 2021 Jul 19.

Stevens-Johnson syndrome post second dose of Pfizer COVID-19 vaccine: a case report

Mohamed Omar Elboraey  1 , Emad El Said Fahim Essa  2
Affiliations
Case Reports

Stevens-Johnson syndrome post second dose of Pfizer COVID-19 vaccine: a case report

Mohamed Omar Elboraey et al. Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Oct.

Abstract

Coronavirus disease 2019 (COVID-19) began in December 2019 and has affected millions of people all over the world. Respiratory illness in the form of severe pneumonia, in addition to multiorgan failure and death, is the clinical spectrum of COVID-19. Although there are no specific therapeutic agents for COVID-19 infection, the COVID-19 vaccine reduces morbidity and mortality associated with COVID-19 infection and is generally well tolerated. We report one potential complication of the Pfizer COVID-19 vaccine: a known case of Stevens-Johnson syndrome (SJS) that occurred after the second dose of the Pfizer COVID-19 vaccine alone without exposure to any other drug. Despite the initial severe adverse reaction, the patient showed a full recovery. Although SJS can be associated with COVID-19 vaccination, it is rare, and the benefits of receiving the vaccination outweigh the potential harms.

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Figures

Fig 1
Fig. 1
Large, deep-red bullae at retromolar area.
Fig 2
Fig. 2
Large oral ulcerations at labial mucosa with yellow crust at lower lip.
Fig 3
Fig. 3
Multiple large oral ulcerations at buccal mucosa.
See this image and copyright information in PMC

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