Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Jan;75(1):230-231.
doi: 10.1002/hep.32103. Epub 2021 Nov 27.

Letter to the Editor: Is the HBsAg response to RO7062931 an antisense effect?

Andrew Vaillant  1
Affiliations
Comment

Letter to the Editor: Is the HBsAg response to RO7062931 an antisense effect?

Andrew Vaillant. Hepatology. 2022 Jan.
No abstract available

PubMed Disclaimer

Comment in

  • Reply.
    Wat C, Gane E, Yuen MF, Pavlovic V, Mueller H, Krippendorff BF, Grippo JF, Ottosen S. Wat C, et al. Hepatology. 2022 Apr;75(4):1050-1051. doi: 10.1002/hep.32113. Epub 2021 Dec 13. Hepatology. 2022. PMID: 34396570 No abstract available.

Comment on

References

REFERENCES

    1. Gane E, Yuen MF, Kim DJ, Chan HL, Surujbally B, Pavlovic V, et al. Clinical study of single stranded oligonucleotide RO7062931 in healthy volunteers and patients with chronic hepatitis B. Hepatology. 2021;74:1795-1808.
    1. Graham MJ, Lee RG, Brandt TA, Tai LJ, Fu W, Peralta R, et al. Cardiovascular and metabolic effects of ANGPTL3 antisense oligonucleotides. N Engl J Med. 2017;377:222-32.
    1. Viney NJ, Guo S, Tai L-J, Baker BF, Aghajan M, Jung SW, et al. Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data. ESC Heart Fail. 2021;8:652-61.
    1. Loomba R, Decaris M, Li KW, Shankaran M, Mohammed H, Matthews M, et al. Discovery of half-life of circulating hepatitis B surface antigen in patients with chronic hepatitis B infection using heavy water labeling. Clin Infect Dis. 2019;69:542-5.
    1. Shekhtman L, Cotler SJ, Hershkovich L, Uprichard SL, Bazinet M, Pantea V, et al. Modelling hepatitis D virus RNA and HBsAg dynamics during nucleic acid polymer monotherapy suggest rapid turnover of HBsAg. Sci Rep. 2020;10:7837.

MeSH terms

Substances

LinkOut - more resources