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Comment
. 2021 Nov:238:343.
doi: 10.1016/j.jpeds.2021.08.006. Epub 2021 Aug 11.

Rapid whole-genome sequencing in critically Ill children: shifting from unease to evidence, education, and equitable implementation

Linda S Franck  1 , David Dimmock  2 , Charlotte Hobbs  2 , Stephen F Kingsmore  2
Affiliations
Comment

Rapid whole-genome sequencing in critically Ill children: shifting from unease to evidence, education, and equitable implementation

Linda S Franck et al. J Pediatr. 2021 Nov.
No abstract available

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Conflict of interest statement

The other authors declare no conflicts of interest.

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  • Reply.
    Lantos JD. Lantos JD. J Pediatr. 2021 Nov;238:343-344. doi: 10.1016/j.jpeds.2021.08.005. Epub 2021 Aug 11. J Pediatr. 2021. PMID: 34390696 No abstract available.

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  • Reply.
    Lantos JD. Lantos JD. J Pediatr. 2021 Nov;238:343-344. doi: 10.1016/j.jpeds.2021.08.005. Epub 2021 Aug 11. J Pediatr. 2021. PMID: 34390696 No abstract available.

References

    1. Lantos JD. Sources of unease about the use of genome sequencing for diagnosing rare diseases in children. J Pediatr 2021; S0022–3476(21)00624–7. - PubMed
    1. Dimmock D, Caylor S, Waldman B, Benson W, Ashburner C, Carmichael JL, et al. Project Baby Bear: Rapid precision care incorporating rWGS in 5 California children’s hospitals demonstrates improved clinical outcomes and reduced costs of care. Am J Hum Genet 2021; 108(7):1231–1238. - PMC - PubMed
    1. Franck LS, Kriz RM, Rego S, Garman K, Hobbs C, Dimmock D. Implementing Rapid Whole-Genome Sequencing in Critical Care: A Qualitative Study of Facilitators and Barriers to New Technology Adoption. J Pediatr 2021; S0022–3476(21)00496–0. - PubMed
    1. Dimmock DP, Clark MM, Gaughran M, Cakici JA, Caylor SA, Clarke C, et al. An RCT of rapid genomic sequencing among seriously ill infants results in high clinical utility, changes in management, and low perceived harm. Am J Hum Genet 2020; 107:942–52. - PMC - PubMed
    1. Cakici JA, Dimmock DP, Caylor SA, Gaughran M, Clarke C, Triplett C, Clark MM, Kingsmore SF, Bloss CS. A prospective study of parental perceptions of rapid whole-genome and -exome sequencing among seriously ill infants. Am J Hum Genet 2020; 107(5):953–962. - PMC - PubMed