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Review
. 2022 Feb 1;112(2):317-334.
doi: 10.1016/j.ijrobp.2021.07.1716. Epub 2021 Aug 12.

Radiation Therapy Across Pediatric Hodgkin Lymphoma Research Group Protocols: A Report From the Staging, Evaluation, and Response Criteria Harmonization (SEARCH) for Childhood, Adolescent, and Young Adult Hodgkin Lymphoma (CAYAHL) Group

Matthew D Hall  1 , Stephanie A Terezakis  2 , John T Lucas  3 , Eve Gallop-Evans  4 , Karin Dieckmann  5 , Louis S Constine  6 , David Hodgson  7 , Jamie E Flerlage  8 , Monika L Metzger  8 , Bradford S Hoppe  9
Affiliations
Review

Radiation Therapy Across Pediatric Hodgkin Lymphoma Research Group Protocols: A Report From the Staging, Evaluation, and Response Criteria Harmonization (SEARCH) for Childhood, Adolescent, and Young Adult Hodgkin Lymphoma (CAYAHL) Group

Matthew D Hall et al. Int J Radiat Oncol Biol Phys. .
No abstract available

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Figures

Fig. 1.
Fig. 1.
Representative field borders/dose distribution for a representative patient with Hodgkin lymphoma and mediastinal involvement (delineated in the center with pink contours) receiving treatment with Mantle field, involved-field and involved-site radiation therapy (yellow) and to residual disease (blue) alone after chemotherapy. The heart (red) and female breast (pink) are also illustrated.
Fig. 2.
Fig. 2.
Computed tomography (CT) simulation fusion with CT component from baseline positron emission tomography/CT scan where patient simulation setup is different from staging scan (arms up vs down), illustrating the difficulty with target volume delineation in the axilla, supraclavicular, and cervical regions.
See this image and copyright information in PMC

References

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    1. Wolden SL, Chen L, Kelly KM, et al. Long-term results of CCG 5942: A randomized comparison of chemotherapy with and without radiotherapy for children with Hodgkin’s lymphoma—A report from the Children’s Oncology Group. J Clin Oncol 2012;30:3174–3180. - PMC - PubMed
    1. Jhawar SR, Rivera-Núñez Z, Drachtman R, Cole PD, Hoppe BS, Parikh RR. Association of combined modality therapy vs chemotherapy alone with overall survival in early-stage pediatric Hodgkin lymphoma. JAMA Oncol 2019;5:689–695. - PMC - PubMed
    1. Tebbi CK, Mendenhall N, London WB, et al. Treatment of stage I, IIA, IIIA1 pediatric Hodgkin disease with doxorubicin, bleomycin, vincristine and etoposide (DBVE) and radiation: A Pediatric Oncology Group (POG) study. Pediatr Blood Cancer 2006;46:198–202. - PubMed
    1. Donaldson SS, Link MP, Weinstein HJ, et al. Final results of a prospective clinical trial with VAMP and low-dose involved-field radiation for children with low-risk Hodgkin’s disease. J Clin Oncol 2007;25:332–337. - PubMed

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