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Case Reports
. 2021 Nov;32(13):1271-1273.
doi: 10.1177/09564624211034974. Epub 2021 Aug 15.

Successful treatment with secnidazole for trichomoniasis in the setting of metronidazole hypersensitivity

Wesley D Kufel  1   2   3 , Elizabeth A Asiago-Reddy  2   3 , Katie A Parsels  3 , Soma Sanyal  2   3 , Jennifer L Coyne  2   3
Affiliations
Case Reports

Successful treatment with secnidazole for trichomoniasis in the setting of metronidazole hypersensitivity

Wesley D Kufel et al. Int J STD AIDS. 2021 Nov.

Abstract

Limited effective treatment options currently exist for trichomoniasis management among patients with metronidazole hypersensitivity. We report a patient with a documented history of metronidazole hypersensitivity who initially was treated with nitazoxanide but demonstrated clinical and microbiological failure. Secnidazole was subsequently used for treatment, which resulted in clinical and microbiological cure without observation of cross-reactivity. Secnidazole may represent a potential treatment option for trichomoniasis in patients with metronidazole hypersensitivity after consultation with an infectious disease specialist.

Keywords: Secnidazole; Trichomonas vaginalis; metronidazole; nitazoxanide; trichomoniasis.

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