Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Oct;28(7):573-575.
doi: 10.1016/j.arcped.2021.06.004. Epub 2021 Jul 9.

SARS-CoV-2-associated Henoch-Schönlein purpura in a 13-year-old girl

Charlotte Borocco  1 , Céline Lafay  2 , Inès Plantard  3 , Jeremy Gottlieb  4 , Isabelle Koné-Paut  2 , Caroline Galeotti  5
Affiliations

SARS-CoV-2-associated Henoch-Schönlein purpura in a 13-year-old girl

Charlotte Borocco et al. Arch Pediatr. 2021 Oct.

Abstract

In the context of the current coronavirus disease 2019 (COVID-19) pandemic, cutaneous lesions are being described. Here, we report on a 13-year-old girl with SARS-CoV-2-associated Henoch-Schönlein purpura and Epstein-Barr virus (EBV) infection. She presented without any respiratory symptoms, only a purpuric skin rash, abdominal pain, low-grade fever, and pharyngitis. Virology tests by polymerase chain reaction (PCR) were positive for SARS-CoV-2 and EBV. The potential association of Henoch-Schönlein purpura and SARS-CoV-2 should be kept in mind in order to reduce the spread of the virus, particularly in children with few respiratory symptoms.

Keywords: Children; Epstein–Barr virus; Henoch–Schönlein purpura; SARS-CoV-2; Vasculitis.

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest The authors have no conflicts of interest relevant to this article to disclose.

Figures

Fig. 1:
Fig. 1
A, B, C: Purpuric lesions of the lower limbs and buttocks in a 13-year-old girl lasting 13 days.
See this image and copyright information in PMC

References

    1. Li X., Xu W., Dozier M. The role of children in the transmission of SARS-CoV2: updated rapid review. J Glob Health. 2020;10 - PMC - PubMed
    1. Wang J.J., Xu Y., Liu F.F. Association of the infectious triggers with childhood Henoch-Schonlein purpura in Anhui province, China. J Infect Public Health. 2020;13:110–117. - PubMed
    1. Hwang H.H., Lim I.S., Choi B.S. Analysis of seasonal tendencies in pediatric Henoch-Schönlein purpura and comparison with outbreak of infectious diseases. Medicine (Baltimore) 2018;97:e12217. - PMC - PubMed
    1. Guissa V.R., Aragão P.A., Marques H.H. Chronic active Epstein-Barr virus infection mimicking Henoch-Schönlein purpura. Acta Reumatol Port. 2010;35:513–517. - PubMed
    1. Kim C.J., Woo Y.J., Kook H. Henoch-Schönlein purpura nephritis associated with Epstein-Barr virus infection in twins. Pediatr Nephrol Berl Ger. 2004;19:247–248. - PubMed