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Review
. 2020 Sep 15;2(3):515-518.
doi: 10.1016/j.jaccao.2020.06.005. eCollection 2020 Sep.

CardioMEMS-Guided CAR T Cell Therapy for Lymphoma in a Patient With Anthracycline-Induced Cardiomyopathy

Anthony J Kanelidis  1 , Jayant Raikhelkar  2 , Gene Kim  1 , Gabriel Sayer  2 , Michael R Bishop  3 , Tamar S Polonsky  1 , Nir Uriel  2
Affiliations
Review

CardioMEMS-Guided CAR T Cell Therapy for Lymphoma in a Patient With Anthracycline-Induced Cardiomyopathy

Anthony J Kanelidis et al. JACC CardioOncol. .
No abstract available

Keywords: CAR, chimeric antigen receptor; CRS, cytokine release syndrome; DLBCL, diffuse large B-cell lymphoma; GDMT, guideline-directed medical therapy; HF, heart failure; LVEF, left ventricular ejection fraction; PAd, pulmonary artery diastolic pressure; R-CHOP, rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone; RHC, right heart catherization; TTE, transthoracic echocardiogram; anthracycline; cardiomyopathy; heart failure; immunotherapy; lymphoma.

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Figures

Figure 1
Figure 1
CardioMEMS Pulmonary Artery Pressure Monitoring CardioMEMS guided diuretic administration and dosing (e.g., intravenous furosemide 20 mg [black triangles] and 40 mg [black squares]) throughout hospitalization. Red line = pulmonary artery (PA) systolic; blue line = PA mean; green line = PA diastolic; CAR = chimeric antigen receptor; MICU = medical intensive care unit.
Figure 2
Figure 2
Chest X-Ray Demonstrating Capillary Leak Secondary to Cytokine Release Syndrome Diffuse pulmonary opacities on chest x-ray, but normal pulmonary artery diastolic pressure of 10 mm Hg based on the CardioMEMS device (denoted by the red arrow).
See this image and copyright information in PMC

References

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