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Review
. 2020 Nov 17;2(4):650-654.
doi: 10.1016/j.jaccao.2020.06.012. eCollection 2020 Nov.

How to Diagnose and Manage Patients With Fluoropyrimidine-Induced Chest Pain: A Single Center Approach

Allison Padegimas  1 , Joseph R Carver  1   2
Affiliations
Review

How to Diagnose and Manage Patients With Fluoropyrimidine-Induced Chest Pain: A Single Center Approach

Allison Padegimas et al. JACC CardioOncol. .
No abstract available

Keywords: 5-FU, 5-fluorouracil; CAD, coronary artery disease; CTA, computed tomography angiogram; CV, cardiovascular; FLOX, bolus dosing 5 fluorouracil, leucovirin, oxaliplatin; FOLFOX, continuous infusion 5 fluorouracil, leucovorin, oxaliplatin; cardiotoxicity; coronary vasospasm; fluoropyrimidine.

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Figures

None
Graphical abstract
Figure 1
Figure 1
Diffuse ST-Segment Elevation From Coronary Vasospasm Electrocardiogram showing diffuse ST-segment elevation during bolus 5-fluorouracil administration attributed to coronary artery vasospasm.
Figure 2
Figure 2
Fluoropyrimidine Cardiac Toxicity and Rechallenge Various cardiac toxicities from fluoropyrimidines, distinct chest pain syndromes attributable to specific agents, and appropriate treatment and/or diagnostic steps. We outline an algorithm using anti-anginal administration for safe fluoropyrimidine rechallenge. ∗According to blood pressure. AMI = acute myocardial infarction; CAD = coronary artery disease CCB = calcium channel blocker; CTA = computed tomography angiography; ECG = electrocardiogram; ER = extended release; 5-FU = 5-fluorouracil.
See this image and copyright information in PMC

References

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