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Comment
. 2021:1:5.
doi: 10.20517/jca.2021.06. Epub 2021 Jun 6.

Hematopoietic JAK2V617F-mediated clonal hematopoiesis: AIM2 understand mechanisms of atherogenesis

Soichi Sano  1 , Kenneth Walsh  2
Affiliations
Comment

Hematopoietic JAK2V617F-mediated clonal hematopoiesis: AIM2 understand mechanisms of atherogenesis

Soichi Sano et al. J Cardiovasc Aging. 2021.
No abstract available

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Conflict of interest statement

Conflicts of interest Both authors declared that there are no conflicts of interest.

Figures

Figure 1.
Figure 1.
Experimental studies of the Jak2V617F mutation in blood and its effects on atherogenesis.
See this image and copyright information in PMC

Comment on

  • The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis.
    Fidler TP, Xue C, Yalcinkaya M, Hardaway B, Abramowicz S, Xiao T, Liu W, Thomas DG, Hajebrahimi MA, Pircher J, Silvestre-Roig C, Kotini AG, Luchsinger LL, Wei Y, Westerterp M, Snoeck HW, Papapetrou EP, Schulz C, Massberg S, Soehnlein O, Ebert B, Levine RL, Reilly MP, Libby P, Wang N, Tall AR. Fidler TP, et al. Nature. 2021 Apr;592(7853):296-301. doi: 10.1038/s41586-021-03341-5. Epub 2021 Mar 17. Nature. 2021. PMID: 33731931 Free PMC article.

References

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    1. Sano S, Wang Y, Yura Y, et al.JAK2 (V617F)-mediated clonal hematopoiesis accelerates pathological remodeling in murine heart failure. JACC Basic Transl Sci 2019;4:684–97. - PMC - PubMed

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