Real-Life Safety of Doravirine in Treatment-Experienced, Virologically Suppressed PLWHIV
- PMID: 34397747
- DOI: 10.1097/QAI.0000000000002730
Real-Life Safety of Doravirine in Treatment-Experienced, Virologically Suppressed PLWHIV
Comment on
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Brief Report: Switching to DOR/3TC/TDF Maintains HIV-1 Virologic Suppression Through Week 144 in the DRIVE-SHIFT Trial.J Acquir Immune Defic Syndr. 2021 Jun 1;87(2):801-805. doi: 10.1097/QAI.0000000000002642. J Acquir Immune Defic Syndr. 2021. PMID: 33633036 Free PMC article. Clinical Trial.
References
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- Kumar P, Johnson M, Molina JM, et al. Switching to doravirine/lamivudine/tenofovir disoproxil fumarate (DOR/3TC/TDF) maintains HIV-1 virologic suppression through week 144 in the DRIVE-SHIFT trial. J Acquir Immune Defic Syndr. 2021;87:801-805.
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- Talwani R, Temesgen Z. Doravirine: a new non-nucleoside reverse transcriptase inhibitor for the treatment of HIV infection. Drugs Today (Barc). 2020;56:113–124.
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- Feng M, Sachs NA, Xu M, et al. Doravirine suppresses common nonnucleoside reverse transcriptase inhibitor-associated mutants at clinically relevant concentrations. Antimicrob Agents Chemother. 2016;60:2241–2247.
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- Fulco PP, Herity LB. Doravirine use in treatment-experienced HIV-positive patients. Ann Pharmacother. 2021;55:127–130.
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- Ankrom W, Yee KL, Sanchez RI, et al. Severe renal impairment has minimal impact on doravirine pharmacokinetics. Antimicrob Agents Chemother. 2018;62:e00326-18.
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