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Case Reports
. 2021 Sep;38(5):1219-1221.
doi: 10.1111/pde.14694. Epub 2021 Aug 16.

Acquired idiopathic generalized anhidrosis: A case series of two Caucasian patients

Alexander T Reid  1 , Lainee Goettsche  1 , Melissa Willis  1 , Jennifer Powers  1 , Kristen G Berrebi  1   2
Affiliations
Case Reports

Acquired idiopathic generalized anhidrosis: A case series of two Caucasian patients

Alexander T Reid et al. Pediatr Dermatol. 2021 Sep.

Abstract

Acquired idiopathic generalized anhidrosis (AIGA) is a rare disorder characterized by insidious or sudden onset of the inability to sweat involving >25% of body surface area in the absence of other neurologic or sweat gland abnormalities and typically affects young, healthy, Asian men. Here, we describe two Caucasian teenagers with the diagnosis. They both had variable responses to prednisone, one in the setting of an elevated ANA, suggesting an autoimmune or inflammatory pathomechanism of the disorder. It is essential the clinician recognizes this rare entity and initiates timely intervention to prevent the serious consequences of hyperpyrexia.

Keywords: AIGA; acquired idiopathic generalized anhidrosis; anhidrosis; sudomotor failure.

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References

REFERENCES

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