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. 2021 Aug 16;22(1):27.
doi: 10.1186/s12863-021-00982-3.

Complete genome sequence of an extensively drug resistant (XDR) M. morganii SMM01 isolated from a patient with urinary and fecal incontinence

Pachi Pulusu Chanakya  1 , Balaram Khamari  1 , Manmath Lama  1 , Arun Sai Kumar Peketi  1 , Prakash Kumar  2 , Valakunja Nagaraja  3   4 , Eswarappa Pradeep Bulagonda  5
Affiliations

Complete genome sequence of an extensively drug resistant (XDR) M. morganii SMM01 isolated from a patient with urinary and fecal incontinence

Pachi Pulusu Chanakya et al. BMC Genom Data. .

Abstract

Objective: M. morganii is a gram-negative, non-lactose fermenting and an opportunistic pathogen frequently associated with nosocomial infections. Although first isolated in 1906 from a pediatric fecal sample, not many M. morganii isolates have been sequenced. The objective of this work is to determine the complete genome sequence of an XDR M. morganii strain (SMM01) isolated from the urine of a patient with urinary and fecal incontinence and to characterize its antimicrobial resistance profile.

Data description: Here, we report the complete genome sequence of M. morganii SMM01 generated from the hybrid assembly of Illumina HiSeq X and Nanopore MinION reads. The assembly is 100% complete with genome size of 39,30,130 bp and GC content of 51%. Genomic features include 3617 CDS, 18 rRNAs, 78 tRNAs, 4 ncRNAs and 60 pseudogenes. Antimicrobial resistance profile was characterized by the presence of genes conferring resistance to aminoglycosides, β-lactams, fluoroquinolones, chloramphenicol, and tetracyclines. Secondary metabolite biosynthetic gene clusters like NRPS, T1PKS, thiopeptide, beta-lactone, and bacteriocin were identified. The genome data described here would be the first complete genome of an Indian M. morganii isolate providing crucial information on antimicrobial resistance patterns, paving the way for further comparative genome analyses.

Keywords: Complete genome and antimicrobial resistance (AMR); Extensively drug resistant (XDR); Hybrid sequencing; M. morganii.

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Conflict of interest statement

The authors declare no competing interests.

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