Commonly used immunosuppressive drugs for kidney diseases and pregnancy: focus on open questions

Abstract

Pregnancy is still a challenge in women with autoimmune diseases or kidney transplantation. In this context, management of the immunosuppressive therapy is critical, but, in spite of more than 60 years of experience, many issues remain open, also because of the difficulty in disentangling, in complex patients, the effect of the disease and of the frequent multiple treatments. For this purpose, we have tried to synthesize the existing knowledge and the unresolved issues, to support counseling and promote patient empowerment.

Keywords: immunologic diseases; immunosuppressive drugs; kidney diseases; kidney transplants; pregnancy.