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. 2022 Apr;134(7-8):286-293.
doi: 10.1007/s00508-021-01924-w. Epub 2021 Aug 17.

Is diversity harmful?-Mixed-brand cardiac implantable electronic devices undergoing magnetic resonance imaging

Christoph Alexander König  1   2 , Florian Tinhofer  1 , Thomas Puntus  1 , Achim Leo Burger  1 , Nikolaus Neubauer  3 , Herbert Langenberger  3 , Kurt Huber  1   4 , Michael Nürnberg  1 , David Zweiker  5   6
Affiliations

Is diversity harmful?-Mixed-brand cardiac implantable electronic devices undergoing magnetic resonance imaging

Christoph Alexander König et al. Wien Klin Wochenschr. 2022 Apr.

Abstract

Background: Many patients with cardiac implantable electronic devices (CIED) undergo magnetic resonance imaging (MRI); however, a relevant proportion have a CIED system that has not been classified as MRI-conditional because of generators and leads from different brands (mixed-brand group). The available data concerning the outcome of these mixed patients undergoing MRI is limited.

Methods: A retrospective single center study, including all patients with CIEDs undergoing MRI between January 2013 until May 2020, was performed. Primary endpoints were defined as death or any adverse event necessitating hospitalization or CIED revision. Secondary endpoints were the occurrence of any sign for beginning device or lead failure or patient discomfort during MRI.

Results: A total of 227 MRI examinations, including 10 thoracic MRIs, were carried out in 158 patients, with 1-9 MRIs per patient. Of the patients 38 underwent 54 procedures in the mixed-brand group and 89 patients underwent 134 MRIs in the MRI-conditional group. Of the patients 31 were excluded since the MRI conditionality could not be determined. No primary endpoints occurred within the mixed-brand group but in 2.2% of the MRI-conditional group (p = 1.000), with 2 patients developing new atrial fibrillation during MRI, of whom one additionally had a transient CIED dysfunction. No secondary endpoints were met in the mixed-brand group compared to 3.4% in the MRI-conditional group (p = 0.554). No complications occurred in the excluded patients.

Conclusion: The complication rate of CIED patients undergoing MRI was low. Patients with a mixed CIED system showed no signs of increased risk of adverse events compared to patients with MRI-conditional CIED systems.

Keywords: Defibrillator; MRI-conditional; Magnetic resonance imaging; Pacemaker; Safety.

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Conflict of interest statement

C.A. König, A.L. Burger, N. Neubauer, H. Langenberger and K. Huber declare that they have no competing interests. D. Zweiker has received speaker fees and/or travel grants from Daiichi Sankyo and research grants from Boston Scientific. F. Tinhofer has received speaker fees from Medtronic. T. Puntus has received speaker fees from Biotronik. M. Nürnberg has received speaker fees from Abbott Laboratories, Microport, Biotronik, Medtronic and Boston Scientific.

Figures

Fig. 1
Fig. 1
Study flowchart. CIED cardiac implantable electric device, MRI magnetic resonance imaging
See this image and copyright information in PMC

References

    1. Sammet S. Magnetic resonance safety. Abdom Radiol (NY) 2016;41(3):444–451. doi: 10.1007/s00261-016-0680-4. - DOI - PMC - PubMed
    1. Eurostat. Medical technologies - examinations by medical imaging techniques (CT, MRI and PET). 2021. https://ec.europa.eu/eurostat/databrowser/view/hlth_co_exam/default/tabl.... Accessed 12 Mai 2021.
    1. Kalin R, Stanton MS. Current clinical issues for MRI scanning of pacemaker and defibrillator patients. Pacing Clin Electrophysiol. 2005;28(4):326–328. doi: 10.1111/j.1540-8159.2005.50024.x. - DOI - PubMed
    1. Faris OP, Shein M. Food and Drug Administration perspective: magnetic resonance imaging of pacemaker and implantable cardioverter-defibrillator patients. Circulation. 2006;114(12):1232–1233. doi: 10.1161/CIRCULATIONAHA.106.647800. - DOI - PubMed
    1. Indik JH, Gimbel JR, Abe H, Alkmim-Teixeira R, Birgersdotter-Green U, Clarke GD, et al. 2017 HRS expert consensus statement on magnetic resonance imaging and radiation exposure in patients with cardiovascular implantable electronic devices. Heart Rhythm. 2017;14(7):e97–e153. doi: 10.1016/j.hrthm.2017.04.025. - DOI - PubMed