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Review
. 2022 Nov;61(11):1325-1335.
doi: 10.1111/ijd.15857. Epub 2021 Aug 17.

Acquired epidermodysplasia verruciformis: clinical presentation and treatment update

Stephen Moore  1   2 , Peter Rady  1 , Stephen Tyring  1
Affiliations
Review

Acquired epidermodysplasia verruciformis: clinical presentation and treatment update

Stephen Moore et al. Int J Dermatol. 2022 Nov.

Abstract

Acquired epidermodysplasia verruciformis (AEV) is a form of epidermodysplasia verruciformis (EV) that is most commonly found in immunocompromised or immunosuppressed patients. EV is commonly associated with human papillomavirus (HPV), which is often found in EV and AEV lesions. Clinical presentation of AEV in patients with organ transplantation, HIV+, congenital HIV+, hematological diseases, and other iatrogenic immunosuppression are reviewed. Treatment options include topical cidofovir, topical retinoids, topical imiquimod, topical glycolic acid, HPV 9-valent vaccine, acitretin, improving cellular immunity, and changing transplant medication to mycophenolate mofetil.

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References

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