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Review
. 2021 Aug 10:13:751-759.
doi: 10.2147/IJWH.S283216. eCollection 2021.

Management of Pregnancy in Women of Advanced Maternal Age: Improving Outcomes for Mother and Baby

Itamar Glick  1 , Ela Kadish  2 , Misgav Rottenstreich  1   3
Affiliations
Review

Management of Pregnancy in Women of Advanced Maternal Age: Improving Outcomes for Mother and Baby

Itamar Glick et al. Int J Womens Health. .

Erratum in

Abstract

Pregnancy at advanced maternal age (age >35 years old) is considered a risk factor for adverse maternal and perinatal outcomes. Yet, pregnancies of advanced maternal age have become more prevalent over the last few decades. Possible maternal complications of pregnancy at age 35 or older include increased risk of spontaneous miscarriage, preterm labor, gestational diabetes mellitus, pre-eclampsia, stillbirth, chromosomal abnormalities, and cesarean delivery. Possible adverse fetal outcomes include infants small for gestational age and intrauterine growth restrictions, low Apgar score, admission to neonatal intensive care units, and an autism spectrum disorder. This paper aims to present an up-to-date review of the literature, summarizing the most current studies and implications for the management of pregnancy of advanced maternal age.

Keywords: advanced maternal age; adverse maternal outcome; adverse perinatal outcome.

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Conflict of interest statement

The authors report no conflicts of interest for this work.

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