Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Aug 3;7(3):20552173211038027.
doi: 10.1177/20552173211038027. eCollection 2021 Jul-Sep.

Cognitive functioning in everyday life: The development of a questionnaire on instrumental activities of daily living in multiple sclerosis

Maureen van Dam  1 , Sietske Am Sikkes  2 , Emma Rammeloo  1 , Evy Reinders  1 , Julia R Jelgerhuis  1 , Jeroen Jg Geurts  1 , Bernhard Mj Uitdehaag  3 , Hanneke E Hulst  1
Affiliations

Cognitive functioning in everyday life: The development of a questionnaire on instrumental activities of daily living in multiple sclerosis

Maureen van Dam et al. Mult Scler J Exp Transl Clin. .

Abstract

Neuropsychological test scores in people with MS (PwMS) do not fully reflect cognitive functioning in daily life. Therefore, we developed a questionnaire based on instrumental activities of daily living (IADL), using the Amsterdam IADL-Q© for Alzheimer's disease as starting point. Forty-eight items were evaluated on relevance and clarity by (inter)national experts (n = 30), PwMS (n = 61) and proxies (n = 30). Consequently, four items were omitted, two items were merged and seven items were added. Fifty items were included in the IADL questionnaire specific to cognitive functioning in MS (the MS-IADL-Q). Future studies are warranted to assess the psychometric properties of the MS-IADL-Q.

Keywords: Amsterdam IADL Questionnaire; MS-IADL-Q; Multiple sclerosis; cognition; instrumental activities of daily living.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Flowchart reflecting the steps taken to develop and evaluate the MS Instrumental Activities of Daily Living Questionnaire (the MS-IADL-Q). PwMS: people with MS.
See this image and copyright information in PMC

References

    1. Sumowski JF, Benedict R, Enzinger C, et al.. Cognition in multiple sclerosis: state of the field and priorities for the future. Neurology 2018; 90: 278–288. - PMC - PubMed
    1. Campbell J, Rashid W, Cercignani M, et al.. Cognitive impairment among patients with multiple sclerosis: associations with employment and quality of life. Postgrad Med J 2017; 93: 143–147. - PubMed
    1. Benedict RH, Walton MK.Evaluating cognitive outcome measures for MS clinical trials: what is a clinically meaningful change? Mult Scler 2012; 18: 1673–1679. - PubMed
    1. Sikkes SA, de Lange-de Klerk ES, Pijnenburg YA, et al.. A new informant-based questionnaire for instrumental activities of daily living in dementia. Alzheimers Dement 2012; 8: 536–543. - PubMed
    1. Oort Q, Dirven L, Meijer W, et al.. Development of a questionnaire measuring instrumental activities of daily living (IADL) in patients with brain tumors: a pilot study. J Neurooncol 2017; 132: 145–153. - PMC - PubMed

LinkOut - more resources