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Comment
. 2021 Sep;70(9):1926-1928.
doi: 10.2337/dbi21-0017. Epub 2021 Aug 20.

Surplus Ceramides: An Added Twist in the Tale of TREM2 and Insulin Resistance

Kierstin L Webster  1 , Lev Becker  2   3
Affiliations
Comment

Surplus Ceramides: An Added Twist in the Tale of TREM2 and Insulin Resistance

Kierstin L Webster et al. Diabetes. 2021 Sep.
No abstract available

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Figures

Figure 1
Figure 1
Inhibiting de novo ceramide production improves metabolic abnormalities in obese Trem2−/− mice. FB, F4/80+CD11b+CD11c−; FBC, F4/80+CD11b+CD11c+.
See this image and copyright information in PMC

Comment on

  • Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages.
    Sharif O, Brunner JS, Korosec A, Martins R, Jais A, Snijder B, Vogel A, Caldera M, Hladik A, Lakovits K, Saluzzo S, Boehm B, Gorki AD, Mesteri I, Lindroos-Christensen J, Tillmann K, Stoiber D, Menche J, Schabbauer G, Bilban M, Superti-Furga G, Esterbauer H, Knapp S. Sharif O, et al. Diabetes. 2021 Sep;70(9):2042-2057. doi: 10.2337/db20-0572. Epub 2021 Feb 24. Diabetes. 2021. PMID: 33627323 Free PMC article.

References

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