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Review
. 2021 Nov:38 Suppl 2:49-57.
doi: 10.1111/pde.14731. Epub 2021 Aug 21.

Dermatologic conditions in Down syndrome

Chenin Ryan  1 , Kishore Vellody  2 , Leah Belazarian  3 , Jillian F Rork  1   4
Affiliations
Review

Dermatologic conditions in Down syndrome

Chenin Ryan et al. Pediatr Dermatol. 2021 Nov.

Abstract

Down syndrome (DS) is the most common chromosomal condition and affects many organs including the skin. Dermatologists are an integral part of the DS care team. This is a review of both common and rare dermatologic conditions in DS. We provide practical strategies for a successful dermatology interview and examination. We explore the downstream effects of trisomy of chromosome 21, in particular on the immune system, and how these insights may enhance our pathophysiologic understanding of their cutaneous conditions.

Keywords: Down syndrome; alopecia areata; dermatologic conditions; dermatology; eczema; folliculitis; hidradenitis suppurativa; melanoma; onychomycosis; psoriasis; scabies; seborrheic dermatitis; skin; skin cancer; trisomy 21; xerosis.

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References

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