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Randomized Controlled Trial
. 2021 Aug 21;22(1):168.
doi: 10.1186/s12875-021-01517-6.

"I must, and I can live with that": a thematic analysis of patients' perspectives on polypharmacy and a digital decision support system for GPs

Collaborators, Affiliations
Randomized Controlled Trial

"I must, and I can live with that": a thematic analysis of patients' perspectives on polypharmacy and a digital decision support system for GPs

Robin Brünn et al. BMC Fam Pract. .

Abstract

Background: To investigate patients' perspectives on polypharmacy and the use of a digital decision support system to assist general practitioners (GPs) in performing medication reviews.

Methods: Qualitative interviews with patients or informal caregivers recruited from participants in a cluster-randomized controlled clinical trial (cRCT). The interviews were transcribed verbatim and analyzed using thematic analysis.

Results: We conducted 13 interviews and identified the following seven themes: the patients successfully integrated medication use in their everyday lives, used medication plans, had both good and bad personal experiences with their drugs, regarded their healthcare providers as the main source of medication-related information, discussed medication changes with their GPs, had trusting relationships with them, and viewed the use of digital decision support tools for medication reviews positively. No unwanted adverse effects were reported.

Conclusions: Despite drug-related problems, patients appeared to cope well with their medications. They also trusted their GPs, despite acknowledging polypharmacy to be a complex field for them. The use of a digital support system was appreciated and linked to the hope that reasons for selecting specific medication regimens would become more comprehensible. Further research with a more diverse sampling might add more patient perspectives.

Trial registration: ClinicalTrials.gov, NCT03430336 . Registered on February 6, 2018.

Keywords: Decision support; Interviews; Patient perspective; Polypharmacy; Primary care; Qualitative study.

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Conflict of interest statement

None.

References

    1. Masnoon N, Shakib S, Kalisch-Ellett L, Caughey GE. What is polypharmacy? A systematic review of definitions. BMC Geriatr. 2017;17:230. doi: 10.1186/s12877-017-0621-2. - DOI - PMC - PubMed
    1. Guthrie B, Makubate B, Hernandez-Santiago V, Dreischulte T. The rising tide of polypharmacy and drug-drug interactions: population database analysis 1995–2010. BMC Med. 2015;13:74. doi: 10.1186/s12916-015-0322-7. - DOI - PMC - PubMed
    1. Boyd CM, Darer J, Boult C, Fried LP, Boult L, Wu AW. Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA. 2005;294:716–24. doi: 10.1001/jama.294.6.716. - DOI - PubMed
    1. Muth C, Kirchner H, van den Akker M, Scherer M, Glasziou PP. Current guidelines poorly address multimorbidity: pilot of the interaction matrix method. J Clin Epidemiol. 2014;67:1242–50. doi: 10.1016/j.jclinepi.2014.07.004. - DOI - PubMed
    1. Duerden M, Avery T, Payne R. Polypharmacy and medicines optimisation: Making it safe and sound. London; 2013.

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