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. 2022 Feb;129(2):233-235.
doi: 10.1016/j.ophtha.2021.08.012. Epub 2021 Aug 20.

Associations between Age-Related Eye Diseases and Charles Bonnet Syndrome in Participants of the Age-Related Eye Disease Study 2: Report Number 26

Jimmy T Le  1 , David Peprah  2 , Elvira Agrón  2 , Tiarnan D L Keenan  2 , Traci E Clemons  3 , Emily Y Chew  2 ; Age-Related Eye Disease Study 2 Research Group  4
Affiliations

Associations between Age-Related Eye Diseases and Charles Bonnet Syndrome in Participants of the Age-Related Eye Disease Study 2: Report Number 26

Jimmy T Le et al. Ophthalmology. 2022 Feb.

Abstract

Eyecare professionals should be aware of Charles Bonnet Syndrome (CBS), a phenomenon involving visual hallucinations in people with visual impairments. We examined prevalence of CBS among AREDS2 participants and its associations with age-related eye diseases.

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Conflict of interest statement

Conflicts of interest

Dr. Le, Chew, Keenan, and Agron are federal employees of the National Eye Institute, National Institutes of Health. No other conflicting relationship exists for any author

Figures

Figure.
Figure.
Drawings hallucinations provided by AREDS2 participants
See this image and copyright information in PMC

Comment in

References

    1. Bonnet C Essai analytique sur les facultés de l’âme. Copenhagen, Denmark: Philibert; 1760.
    1. Teunisse RJ, Cruysberg JR, Hoefnagels WH, Verbeek AL, Zitman FG. Visual hallucinations in psychologically normal people: Charles Bonnet’s syndrome. Lancet. 1996;347(9004):794–797. - PubMed
    1. Age-Related Eye Disease Study Research Group, Chew EY, Clemons T, et al. The Age-Related Eye Disease Study 2 (AREDS2): study design and baseline characteristics (AREDS2 report number 1). Ophthalmology. 2012;119(11):2282–2289. - PMC - PubMed
    1. Niazi S, Krogh Nielsen M, Singh A, Sorensen TL, Subhi Y. Prevalence of Charles Bonnet syndrome in patients with age-related macular degeneration: systematic review and meta-analysis. Acta Ophthalmol. 2020;98(2):121–131. - PubMed
    1. Subhi Y, Schmidt DC, Bach-Holm D, Kolko M, Singh A. Prevalence of Charles Bonnet syndrome in patients with glaucoma: a systematic review with meta-analyses. Acta Ophthalmol. 2020. - PubMed

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