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Observational Study
. 2022 Jan;42(1):229-238.
doi: 10.1007/s10792-021-02017-3. Epub 2021 Aug 22.

MacuFix® versus Amsler grid for metamorphopsia categorization for macular diseases

Daniela Claessens  1 , Parul Ichhpujani  2 , Rohan Bir Singh  3   4
Affiliations
Observational Study

MacuFix® versus Amsler grid for metamorphopsia categorization for macular diseases

Daniela Claessens et al. Int Ophthalmol. 2022 Jan.

Abstract

Purpose: Macular diseases often lead to metamorphopsia, which is traditionally tested using the Amsler grid. This study evaluates a novel method for assessing metamorphopsia, based on the software AMD-A Metamorphopsia Detector, application MacuFix®.

Methods: In this observational study, the usability of a new smartphone-based testing method to assess metamorphopsia was evaluated in 45 patients experiencing metamorphopsia in at least one eye using the questionnaire "System Usability Score (SUS)." Additionally, the diagnostic adherence of self-monitoring with the Amsler grid was compared to self-monitoring with the novel software MacuFix®.

Results: The average score of the SUS questionnaire in this study was 76.7 ± 15.5, corresponding to the "good" score on the grading scale. The average interval between two home administered tests was significantly shorter (6 days) when the application was used as compared to using the Amsler grid (19 days). The odds ratio of the frequency of patients using the application to the patients using the home test was 4.

Conclusion: MacuFix® application can help in effective home monitoring of macular function as high user satisfaction and increased testing frequency was observed in its use in patients with macular diseases.

Trial registration: ClinicalTrials.gov NCT04347564.

Keywords: Adherence; Age-related macular degeneration; Diabetic macular edema; Metamorphopsia; Smartphone-based application; Usability.

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Conflict of interest statement

Parul Ichhpujani and Rohan Bir Singh certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript. Daniela Claessens is co- owner and medical advisor for app4eyes GmbH&CoKG and holds a patent (German Patent DE102019205318).

Figures

Fig. 1
Fig. 1
MacuFix used on a smartphone
Fig. 2
Fig. 2
SD-OCT of the left eye of Subject No. 45 with medium drusen and no pigmentary abnormalities and an example of the distortion difference 1: The upper left quadrant contains lines that are more distorted than those in the remaining three quadrants
Fig. 3
Fig. 3
SD-OCT Subject No. 14 left eye and Macufix distortion difference 2
Fig. 4
Fig. 4
SD-OCT Subject No. 10 left eye and MacuFix distortion difference 4
Fig. 5
Fig. 5
SD-OCT Subject No. 8 left eye and MacuFix distortion difference 5
See this image and copyright information in PMC

References

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