Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Aug 6:12:653624.
doi: 10.3389/fpsyt.2021.653624. eCollection 2021.

Commentary on Singh et al. (2020) Postzygotic Somatic Mutations in the Human Brain Expand the Threshold-Liability Model of Schizophrenia

Peter S Spencer  1 , Glen E Kisby  2
Affiliations
Comment

Commentary on Singh et al. (2020) Postzygotic Somatic Mutations in the Human Brain Expand the Threshold-Liability Model of Schizophrenia

Peter S Spencer et al. Front Psychiatry. .
No abstract available

Keywords: amyotrophic lateral sclerosis; brain DNA damage; environmental somatic mutagen; methylazoxymethanol; schizophrenia.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Comment on

References

    1. Spencer PS, Palmer VS, Kisby GE. Western Pacific ALS-PDC: evidence implicating cycad genotoxins. J Neurol Sci. (2020) 419:117185. 10.1016/j.jns.2020.117185 - DOI - PubMed
    1. Kisby GE, Ellison M, Spencer PS. Content of the neurotoxins cycasin (methylazoxymethanol β-D-glucoside) and BMAA (β-N-methylamino-L-alanine) in cycad flour prepared by Guam Chamorros. Neurology. (1992) 42:1336–40. 10.1212/WNL.42.7.1336 - DOI - PubMed
    1. Rana I, Rieswijk L, Steinmaus C, Zhang L. Formaldehyde and brain disorders: a meta-analysis and bioinformatics approach. Neurotox Res. (2021) 20:320. 10.1007/s12640-020-00320-y - DOI - PMC - PubMed
    1. Román GC. Neuroepidemiology of amyotrophic lateral sclerosis: clues to aetiology and pathogenesis. J Neurol Neurosurg Psychiatry. (1996) 61:131–7. 10.1136/jnnp.61.2.131 - DOI - PMC - PubMed
    1. Spencer PS. Etiology of retinal and cerebellar pathology in Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex. Eye Brain. (2020) 12:97–104. 10.2147/EB.S260823 - DOI - PMC - PubMed

LinkOut - more resources